Michael E. DeBakey High School for Health Professions is a medical secondary school located in the Medical Center area of Houston, Texas, United States. It is a part of the Houston Independent School District.

Hilton Head Island High School is a public high school within the Beaufort County School District, located in Hilton Head Island, South Carolina.

Burlingame High School is a public high school in Burlingame, California.

Edgemont Junior – Senior High School is a high school in Greenville, New York, serving students in grades 7 -12. 

Westford Academy is the public high school for the town of Westford, Massachusetts. It was incorporated in 1792 and is one of the oldest public high schools in the United States.

iSchool High at University Park (High School) is a tuition-free public charter school located in Houston, Texas.

St. Paul's School for Girls is an independent college-preparatory school in Brooklandville, Maryland, founded in 1959 to replace an older girls' school which had been closed.

Hayesville High School is a school located in Hayesville, North Carolina and is part of the Clay County School District.

Central Wake High School is located in Raleigh, North Carolina.

Marlboro High School is a four-year comprehensive public high school located in Marlboro Township, New Jersey.

Brooklyn Prospect High School is a public charter school located in Brooklyn, New York.

Midwood High School is a high school located in Brooklyn, New York City, administered by the New York City Department of Education.

Auburndale High School is a public high school located in Auburndale, Florida.

Bonita Vista High School is a public four-year high school in Chula Vista, California.

Leonia High School is a four-year comprehensive public high school serving students in ninth through twelfth grade from the Borough of Leonia in Bergen County, New Jersey.

Smithfield-Selma High School is a public high school located in Smithfield, North Carolina. It is locally referred to as simply "SSS". The school is part of Johnston County Schools.

Washington High School is located in Washington, North Carolina.

Wayne Country Day School is a private school located in Goldsboro, North Carolina.

Charles B. Aycock High School is a public high school in Wayne County, North Carolina.

Charlotte Catholic is a diocesan high school in Charlotte, North Carolina, founded in 1955. The school is accredited by the Southern Association of Colleges and Schools. It is located in the Roman Catholic Diocese of Charlotte.